Pharmaceutics Solved MCQs

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   1. What is the primary goal of pharmaceutics?
      a) To discover new drugs
      b) To design and manufacture dosage forms
      c) To study drug mechanisms
      d) To analyze drug interactions
      Answer: b) To design and manufacture dosage forms

   2. Which of the following is a solid dosage form?
      a) Syrup
      b) Tablet
      c) Injection
      d) Emulsion
      Answer: b) Tablet

   3. What is the purpose of an excipient in a formulation?
      a) To provide therapeutic effect
      b) To enhance stability, bioavailability, or patient acceptability
      c) To act as the active ingredient
      d) To replace the active ingredient
      Answer: b) To enhance stability, bioavailability, or patient acceptability

   4. Which of the following is a hydrophilic matrix system used in controlled-release formulations?
      a) Ethyl cellulose
      b) Hydroxypropyl methylcellulose (HPMC)
      c) Eudragit
      d) Polylactic acid
      Answer: b) Hydroxypropyl methylcellulose (HPMC)

   5. What is the process of converting a drug into a fine powder called?
      a) Granulation
      b) Milling
      c) Compression
      d) Coating
      Answer: b) Milling

   6. Which of the following is a unit operation in tablet manufacturing?
      a) Distillation
      b) Granulation
      c) Filtration
      d) Crystallization
      Answer: b) Granulation

   7. What is the purpose of a disintegrant in a tablet formulation?
      a) To bind the tablet ingredients
      b) To facilitate tablet breakup in the gastrointestinal tract
      c) To provide a sweet taste
      d) To increase tablet hardness
      Answer: b) To facilitate tablet breakup in the gastrointestinal tract

   8. Which of the following is a common binder used in tablet formulations?
      a) Lactose
      b) Microcrystalline cellulose
      c) Povidone
      d) Magnesium stearate
      Answer: c) Povidone

   9. What is the role of a lubricant in tablet manufacturing?
      a) To enhance drug dissolution
      b) To reduce friction during tablet compression
      c) To improve tablet disintegration
      d) To increase tablet hardness
      Answer: b) To reduce friction during tablet compression

   10. Which of the following is an example of a sustained-release dosage form?
       a) Immediate-release tablet
       b) Transdermal patch
       c) Effervescent tablet
       d) Syrup
       Answer: b) Transdermal patch

   11. What is the purpose of enteric coating?
       a) To enhance drug absorption in the stomach
       b) To prevent drug release in the stomach
       c) To improve tablet hardness
       d) To provide a sweet taste
       Answer: b) To prevent drug release in the stomach

   12. Which of the following is a parenteral dosage form?
       a) Capsule
       b) Injection
       c) Syrup
       d) Ointment
       Answer: b) Injection

   13. What is the primary function of a preservative in a formulation?
       a) To enhance drug absorption
       b) To prevent microbial growth
       c) To improve drug stability
       d) To provide color
       Answer: b) To prevent microbial growth

   14. Which of the following is a common preservative used in ophthalmic preparations?
       a) Benzalkonium chloride
       b) Sodium benzoate
       c) Propylene glycol
       d) Glycerin
       Answer: a) Benzalkonium chloride

   15. What is the purpose of a surfactant in an emulsion?
       a) To stabilize the emulsion
       b) To increase viscosity
       c) To provide color
       d) To enhance drug absorption
       Answer: a) To stabilize the emulsion

   16. Which of the following is an example of an oil-in-water (O/W) emulsion?
       a) Butter
       b) Milk
       c) Margarine
       d) Cream
       Answer: b) Milk

   17. What is the primary purpose of a suspending agent in a suspension?
       a) To prevent settling of particles
       b) To enhance drug absorption
       c) To provide color
       d) To improve taste
       Answer: a) To prevent settling of particles

   18. Which of the following is a common suspending agent?
       a) Sodium carboxymethyl cellulose
       b) Lactose
       c) Magnesium stearate
       d) Talc
       Answer: a) Sodium carboxymethyl cellulose

   19. What is the purpose of a plasticizer in film coating?
       a) To increase film flexibility
       b) To enhance drug release
       c) To improve tablet hardness
       d) To provide color
       Answer: a) To increase film flexibility

   20. Which of the following is a common plasticizer used in film coating?
       a) Polyethylene glycol (PEG)
       b) Hydroxypropyl methylcellulose (HPMC)
       c) Titanium dioxide
       d) Talc
       Answer: a) Polyethylene glycol (PEG)

   21. What is the purpose of a dissolution test?
       a) To measure the rate of drug release from a dosage form
       b) To determine the hardness of a tablet
       c) To measure the viscosity of a liquid
       d) To assess the stability of a formulation
       Answer: a) To measure the rate of drug release from a dosage form

   22. Which of the following is a common dissolution medium?
       a) Water
       b) Ethanol
       c) Acetone
       d) Ether
       Answer: a) Water

   23. What is the purpose of a stability study in pharmaceutics?
       a) To determine the shelf life of a product
       b) To measure the hardness of a tablet
       c) To assess the taste of a formulation
       d) To determine the color of a product
       Answer: a) To determine the shelf life of a product

   24. Which of the following is a common accelerated stability testing condition?
       a) 25°C and 60% relative humidity
       b) 40°C and 75% relative humidity
       c) 60°C and 90% relative humidity
       d) 80°C and 100% relative humidity
       Answer: b) 40°C and 75% relative humidity

   25. What is the purpose of a bioavailability study?
       a) To measure the rate and extent of drug absorption
       b) To determine the hardness of a tablet
       c) To assess the taste of a formulation
       d) To measure the viscosity of a liquid
       Answer: a) To measure the rate and extent of drug absorption

   26. Which of the following factors can affect bioavailability?
       a) Drug solubility
       b) Particle size
       c) Formulation design
       d) All of the above
       Answer: d) All of the above

   27. What is the purpose of a granulation process in tablet manufacturing?
       a) To improve flow properties and compressibility of powders
       b) To enhance drug dissolution
       c) To increase tablet hardness
       d) To provide a sweet taste
       Answer: a) To improve flow properties and compressibility of powders

   28. Which of the following is a wet granulation method?
       a) Dry mixing
       b) Roller compaction
       c) High-shear granulation
       d) Direct compression
       Answer: c) High-shear granulation

   29. What is the purpose of a capsule in drug delivery?
       a) To enclose a dose of medication in a soluble shell
       b) To enhance drug absorption
       c) To improve tablet hardness
       d) To provide a sweet taste
       Answer: a) To enclose a dose of medication in a soluble shell

   30. Which of the following is a common capsule material?
       a) Gelatin
       b) Cellulose
       c) Starch
       d) Lactose
       Answer: a) Gelatin

   31. What is the purpose of a suppository?
       a) To deliver drugs through the rectal or vaginal route
       b) To enhance drug absorption in the stomach
       c) To improve tablet hardness
       d) To provide a sweet taste
       Answer: a) To deliver drugs through the rectal or vaginal route

   32. Which of the following is a common suppository base?
       a) Cocoa butter
       b) Lactose
       c) Talc
       d) Magnesium stearate
       Answer: a) Cocoa butter

   33. What is the purpose of a transdermal patch?
       a) To deliver drugs through the skin
       b) To enhance drug absorption in the stomach
       c) To improve tablet hardness
       d) To provide a sweet taste
       Answer: a) To deliver drugs through the skin

   34. Which of the following is a common drug delivered via a transdermal patch?
       a) Nicotine
       b) Paracetamol
       c) Aspirin
       d) Ibuprofen
       Answer: a) Nicotine

   35. What is the purpose of a lyophilization process?
       a) To remove water from heat-sensitive products
       b) To enhance drug absorption
       c) To improve tablet hardness
       d) To provide a sweet taste
       Answer: a) To remove water from heat-sensitive products

   36. Which of the following is a lyophilized product?
       a) Freeze-dried injectables
       b) Tablets
       c) Capsules
       d) Syrups
       Answer: a) Freeze-dried injectables

   37. What is the purpose of a sterilization process?
       a) To eliminate microorganisms from a product
       b) To enhance drug absorption
       c) To improve tablet hardness
       d) To provide a sweet taste
       Answer: a) To eliminate microorganisms from a product

   38. Which of the following is a common sterilization method for heat-sensitive products?
       a) Autoclaving
       b) Filtration
       c) Dry heat
       d) Moist heat
       Answer: b) Filtration

   39. What is the purpose of a quality control test in pharmaceutics?
       a) To ensure the product meets specified standards
       b) To enhance drug absorption
       c) To improve tablet hardness
       d) To provide a sweet taste
       Answer: a) To ensure the product meets specified standards

   40. Which of the following is a quality control test for tablets?
       a) Dissolution test
       b) Viscosity test
       c) pH test
       d) Color test
       Answer: a) Dissolution test

   41. What is the purpose of a pharmacokinetic study?
       a) To study the absorption, distribution, metabolism, and excretion of a drug
       b) To measure the hardness of a tablet
       c) To assess the taste of a formulation
       d) To measure the viscosity of a liquid
       Answer: a) To study the absorption, distribution, metabolism, and excretion of a drug

   42. Which of the following is a pharmacokinetic parameter?
       a) Half-life
       b) Hardness
       c) Viscosity
       d) pH
       Answer: a) Half-life

   43. What is the purpose of a pharmacodynamic study?
       a) To study the biochemical and physiological effects of a drug
       b) To measure the hardness of a tablet
       c) To assess the taste of a formulation
       d) To measure the viscosity of a liquid
       Answer: a) To study the biochemical and physiological effects of a drug

   44. Which of the following is a pharmacodynamic parameter?
       a) Efficacy
       b) Hardness
       c) Viscosity
       d) pH
       Answer: a) Efficacy

   45. What is the purpose of a bioavailability enhancer?
       a) To improve the absorption of poorly soluble drugs
       b) To enhance tablet hardness
       c) To provide a sweet taste
       d) To improve drug stability
       Answer: a) To improve the absorption of poorly soluble drugs

   46. Which of the following is a bioavailability enhancer?
       a) Cyclodextrin
       b) Lactose
       c) Talc
       d) Magnesium stearate
       Answer: a) Cyclodextrin

   47. What is the purpose of a sustained-release formulation?
       a) To provide controlled drug release over an extended period
       b) To enhance drug absorption
       c) To improve tablet hardness
       d) To provide a sweet taste
       Answer: a) To provide controlled drug release over an extended period

   48. Which of the following is a mechanism of sustained-release drug delivery?
       a) Diffusion
       b) Dissolution
       c) Osmosis
       d) All of the above
       Answer: d) All of the above

   49. What is the purpose of a targeted drug delivery system?
       a) To deliver drugs to a specific site in the body
       b) To enhance drug absorption
       c) To improve tablet hardness
       d) To provide a sweet taste
       Answer: a) To deliver drugs to a specific site in the body

   50. Which of the following is an example of a targeted drug delivery system?
       a) Liposomes
       b) Tablets
       c) Capsules
       d) Syrups
       Answer: a) Liposomes