Antibiotics solved MCQs

 

Antibiotics Multiple Choice Questions MCQs with Answers

1. The first drug of choice in gonorrhoea is:
a. Cephalosporin
b. Sulphonamides
c. Penicillin
d. Sulfone
Answer: c. Penicillin

2. Penicillin was accidentally discovered in:
a. 1922
b. 1924
c. 1921
d. 1928
Answer: d. 1928

3. Which of the following statement are true regarding cefepime:
a. It is 4th generation Cephalosporin
b. Once day dose is sufficient
c. It has no antipseudomonal
d. It is prodrug
Answer: a. It is 4th generation Cephalosporin

4. The antimicrobial activity of penicillin is due to:
a. Thiazolidine
b. Betalactam ring
c. 6-aminopenicillin acid
d. None
Answer: c. 6-aminopenicillin acid

5. Cyclosporine is used for:
a. Allergies
b. Angina
c. Prevention of transport rejection
d. Steroid deficiency
Answer: c. Prevention of transport rejection

6. The plasma half-life of penicillin-G is longer in the newborn because their:
a. Plasma protein level is low
b. Drug metabolizing
c. Glomerular filtration rate is low
d. Tubular transport mechanisms are not well developed
Answer: d. Tubular transport mechanisms are not well developed

7. The antibiotic with a high therapeutic index:
a. Streptomycin
b. Doxy
c. Cephalexin
d. Polymyxin B
Answer: c. Cephalexin

8. Which antibiotic should be avoided in patients with liver disease:
a. Chlortetracycline
b. Cotrimoxazole
c. Cephalexin
d. Ethambutol
Answer: a. Chlortetracycline

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9. Which of the following is not semisynthetic penicillin?
a. Procaine penicillin
b. Ampicillin
c. Cloxacillin
d. Carbenicillin
Answer: a. Procaine penicillin

10. The most frequent effect of oral Ampicillin is?
a. Nausea and vomiting
b. Loose motion
c. Constipation
d. Urticaria
Answer: b. Loose motion

11. Which of the following causes the infection that is cured by Cloxacillin?
a. Staphylococcus
b. Streptococci
c. Gonococci
d. All of mentioned above
Answer: a. Staphylococcus

12. Which of the following is the most potent tetracycline antibiotic?
a. Demeclocycline
b. Methacycline
c. Minocycline
d. Doxycycline
Answer: c. Minocycline

13. Antibiotics are medicines that help stop infections caused by:
a. Virus
b. Bacteria
c. Protozoans
d. Amoeba
Answer: b. Bacteria

14. The word antibiotic means:
a. Life-giving
b. Against life
c. Birth giving
d. Loss
Answer: b. Against life

15. During which phase of growth of Penicillium chrysogenum maximum antibiotic production takes place?
a. First
b. Second
c. Third
d. Fourth
Answer: b. Second

16. What infection do antibiotics treat?
a. Bacterial infections
b. Viral infection
c. Fungal infection
d. Parasitic infection
Answer: a. Bacterial infections

17. Which of the following species is used for producing tetracycline??
a. Streptomyces griseus
b. Streptomyces venezuelae
c. Streptomyces aureofaciens
d. Streptomyces griseoflavus
Answer: c. Streptomyces aureofaciens

18. What is the primary concern with the use of beta-lactams for sepsis?
a. Food poisoning
b. Aplastic anemia
c. Allergic reactions
d. Hearing impairment
Answer: c. Allergic reactions

19. Choose the correct statement about Penicillin at Acidic pH:
a. Food poisoning
b. Penicillin remains in the solvent phase
c. Penicillin remains in the aqueous phase
d. None of these
Answer: b. Penicillin remains in the solvent phase

20. Streptomycin is produced by which of the following Organisms??
a. Streptomyces noursei
b. Streptomyces nodosus
c. Streptomyces fradiae
d. Streptomyces griseus
Answer: d. Streptomyces griseus

21. Which antibiotic is the drug of choice for most odontogenic infections?
a. Tetracycline
b. Trimethoprim
c. Ciprofloxacin
d. Penicillin
Answer: d. Penicillin

22. Multidrug resistance is most closely related to:
a. Viruses
b. Transformation
c. Plasmids
d. Cell chromosome
Answer: c. Plasmids

23. Which of the Following antibiotics act as folate antagonist against gram-positive and gram-negative organisms?
a. Tetracycline
b. Trimethoprim
c. Ciprofloxacin
d. Penicillin
Answer: b. Trimethoprim

24. Which of the Following antibiotics acts to inhibit bacterial protein and DNA synthesis?
a. Tetracycline
b. Trimethoprim
c. Ciprofloxacin
d. Penicillin
Answer: a. Tetracycline