MITOCHONDRIA
(1). Which of the following cell organelle can be viewed by a light microscope?
a. Ribosome
b. Endoplasmic Reticulum
c. Golgi
d. Mitochondria
b. Endoplasmic Reticulum
c. Golgi
d. Mitochondria
(2). Which of the following statement about mitochondria is NOT true?
a. Size and shape of mitochondria varies in a cell
b. Mitochondria in the cell can fuse with one another
c. Large mitochondria in the call can split into two
d. In all cells, one mitochondria will be exceptionally larger than others
b. Mitochondria in the cell can fuse with one another
c. Large mitochondria in the call can split into two
d. In all cells, one mitochondria will be exceptionally larger than others
(3). Nebenkern of insect sperm cells is a modified _________.
a. Nucleus
b. Golgi apparatus
c. Mitochondria
d. Centrosome
b. Golgi apparatus
c. Mitochondria
d. Centrosome
(4). Mitochondria in the human sperm cell are occupied at _________.
a. Sperm head
b. Mid piece
c. Sperm tail
d. No mitochondria in the sperms
b. Mid piece
c. Sperm tail
d. No mitochondria in the sperms
(5). Which of the following statement is true regarding the membrane system of mitochondria?
a. Chemical composition of both inner and outer membrane of mitochondria are same
b. Outer membrane contain more proteins/lipid ratio (by weight) than inner membrane
c. Inner membrane contain more proteins/lipid ratio (by weight) than outer membrane
d. Phospholipids are completely absent on the outer membrane of mitochondria
b. Outer membrane contain more proteins/lipid ratio (by weight) than inner membrane
c. Inner membrane contain more proteins/lipid ratio (by weight) than outer membrane
d. Phospholipids are completely absent on the outer membrane of mitochondria
(6). Which of the following membrane lipid constituent can be considered as the lipid marker of inner mitochondrial membrane?
a. Lecithin
b. Cardiolipin
c. Ceramide
d. Sphingo-ceramide
b. Cardiolipin
c. Ceramide
d. Sphingo-ceramide
(7). The only other place where cardiolipin can be found naturally other than mitochondrial inner membrane is________.
a. Inner membrane of Golgi apparatus
b. Apoptosome
c. Bacterial plasma membrane
d. Membrane of glyoxysome
b. Apoptosome
c. Bacterial plasma membrane
d. Membrane of glyoxysome
(8). Which of the following statement regarding the distribution of cholesterol is true in the membrane system of mitochondria?
a. Cholesterol is completely absent in mitochondrial membrane
b. Cholesterol is absent in the inner membrane
c. Cholesterol is present only in the inner membrane
d. Cholesterol is present in both inner and outer membrane
b. Cholesterol is absent in the inner membrane
c. Cholesterol is present only in the inner membrane
d. Cholesterol is present in both inner and outer membrane
(9). Mitochondrial membrane system processes a variety of porin proteins which allow the passage of selective molecules. Which of the following statement is true regarding the porin protein in the mitochondrial membrane system?
a. Mitochondrial outer membrane possess porins but they lack the usual beta barrel structure of the usual porins
b. Both inner and outer mitochondrial membrane possess porin proteins
c. Only the inner mitochondrial membrane possess porin proteins
d. Many porin proteins which are structurally similar to the porins of bacterial cells are present in the outer membrane of mitochondria
b. Both inner and outer mitochondrial membrane possess porin proteins
c. Only the inner mitochondrial membrane possess porin proteins
d. Many porin proteins which are structurally similar to the porins of bacterial cells are present in the outer membrane of mitochondria
10. ATP, NAD and CoA can be ___________.
a. Freely transported through both outer and inner membrane of mitochondria
b. Freely transported through the outer membrane of mitochondria
c. Freely transported through the inner membrane of mitochondria
d. Cannot be transported freely through outer and inner membrane of mitochondria
b. Freely transported through the outer membrane of mitochondria
c. Freely transported through the inner membrane of mitochondria
d. Cannot be transported freely through outer and inner membrane of mitochondria
11. Cellular organelle(s) involved in the regulation of Ca2+ level in the cell ________.
a. Mitochondria
b. Endoplasmic Reticulum
c. Endoplasmic Reticulum and Mitochondria
d. Mitochondria and vesicles
b. Endoplasmic Reticulum
c. Endoplasmic Reticulum and Mitochondria
d. Mitochondria and vesicles
12. The only enzyme in citric acid cycle (Kreb’s cycle) which is attached to the inner mitochondrial membrane is:
a. Succinate dehydrogenase
b. NADPH dehydrogenase
c. Isocitrate dehydrogenase
d. Malate dehydrogenase
b. NADPH dehydrogenase
c. Isocitrate dehydrogenase
d. Malate dehydrogenase
13. Which of the following can be used as an enzyme marker for inner mitochondrial membrane?
a. Succinate dehydrogenase
b. ATP synthase
c. Succinyl Co-A synthase
d. Cardiolipin
b. ATP synthase
c. Succinyl Co-A synthase
d. Cardiolipin
14. Which of the following is a mobile electron carrier in the mitochondrial electron transport system?
a. NADH dehydrogenase
b. FADH Dehydrogenase
c. Ubiquinone
d. Succinate dehydrogenase
b. FADH Dehydrogenase
c. Ubiquinone
d. Succinate dehydrogenase
15. Which of the following cellular event is NOT directly involved with mitochondria?
a. Apoptosis
b. ATP synthesis
c. Controlling cell cycle
d. Protein degradation
b. ATP synthesis
c. Controlling cell cycle
d. Protein degradation
16. Which of the following statement is NOT true about mitochondria?
a. Hepatocytes have more than 2000 mitochondria per cell
b. RBC completely lack mitochondria
c. Sperm cells of Insects completely lack mitochondria
d. Mitochondrial number may change in each cell of a species
b. RBC completely lack mitochondria
c. Sperm cells of Insects completely lack mitochondria
d. Mitochondrial number may change in each cell of a species
17. Example for autonomous organelle(s):
a. Mitochondria
b. Chloroplast
c. Mitochondria and chloroplast
d. Chloroplast, mitochondria and Golgi
b. Chloroplast
c. Mitochondria and chloroplast
d. Chloroplast, mitochondria and Golgi
18. Pick-out the odd one:
a. Kearns-Sayre syndrome
b. Tay-sach syndrome
c. MELAS syndrome
d. Leber’s hereditary optic neuropathy
b. Tay-sach syndrome
c. MELAS syndrome
d. Leber’s hereditary optic neuropathy
19. Mitochondrial DNA (mtDNA) is considered as one of the best marker tool for population biologists and evolutionary biologists. The reason for this is:
a. Mitochondrial DNA undergo spontaneous mutation
b. Mitochondrial DNA can be easy isolated
c. Mitochondrial genes are specific to mtDNA
d. Absence of genetic recombination in mtDNA
b. Mitochondrial DNA can be easy isolated
c. Mitochondrial genes are specific to mtDNA
d. Absence of genetic recombination in mtDNA
20. Cyanide is a mitochondrial toxin. The mechanism of action of cyanide is by inhibiting:
a. NADH dehydrogenase
b. Succinate dehydrogenase
c. Cytochrome c oxidase
d. ATP synthase
b. Succinate dehydrogenase
c. Cytochrome c oxidase
d. ATP synthase
ANSWERS
1. Ans. (d). Mitochondria.
2. Ans. (d). In all cells, one mitochondria will be exceptionally larger than others
3. Ans. (c). Mitochondria
4. Ans. (b). Mid piece
5. Ans. (c). Inner membrane contain more proteins/lipid ratio (by weight) than outer membrane
6. Ans. (b). Cardiolipin
7. Ans. (c). Bacterial plasma membrane
8. Ans. (b). Cholesterol is absent in the inner membrane of mitochondria
9. Ans. (d). Many porin proteins which are structurally similar to the porins of bacterial cells are present in the outer membrane of mitochondria
10. Ans. (b). Freely transported through the outer membrane of mitochondria
11. Ans. (c). Endoplasmic Reticulum and Mitochondria
12. Ans. (a). Succinate dehydrogenase
13. Ans. (a). Succinate dehydrogenase
14. Ans. (c). Ubiquinone
15. Ans. (d). Protein degradation
16. Ans. (c). Sperm cell of insects completely lack mitochondria
17. Ans. (c). Mitochondria and Chloroplast
18. Ans. (b). Tay-sach syndrome
19. Ans. (d). Absence of genetic recombination in mtDNA
20. Ans. (c). Cytochrome c oxidase
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